Sleep Breath 2000; 4(4): 169-172
DOI: 10.1055/s-2000-12545
Copyright © 2000 by Thieme Medical Publishers, Inc., 333 Seventh Avenue, New York, NY 10001, USA. Tel.: +1(212) 584-4662

Improvement of CPAP Therapy by a Self-Adjusting System

Katrin Pilz, Stefan Thalhofer, Philipp Meissner, Peter Dorow
  • DRK Hospital Mark Brandenburg, Department of Respiratory and Critical Care Medicine, Humboldt University of Berlin, Berlin, Germany
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31. Dezember 2000 (online)


The first generation of Auto CPAP devices caused respiratory arousal by apnoes, hypopnoeas, incomplete obstructions and pressurechanges. The new, second generation of CPAP devices which is based on forced oscillation technique will change the pressure with slower velocity and before the respiratory arousal reaction will occur (1, 9, 10). Fifty patients with severe sleep apnoea (AHI 66±26 /h) were treated with both, constant- CPAP (continous positive airway pressure) or Auto CPAP under polysomnographic control in a randomised order. The Auto CPAP based on forced oscillation technique reduced the number of apnoeas and hypopnoeas as did most of the other Auto CPAP systems to AHI 2.5±5.9 /h (p<0.05). In comparison to Auto CPAP of the first generation it also decreased the number of respiratory arousal reactions caused by apnoeas and hypopnoeas. However there is still a significant difference to number of arousal detected with constant CPAP (p<0.01). In conclusion although the new generation of Auto CPAP reduced the number of respiratory arousals compared to first generation, we did not find a therapeutical benefit for patients with severe SAS.


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