Zusammenfassung
Die Arbeit stellt, ausgehend von der wachsenden Notwendigkeit von Wirkungsnachweisen
auch für das Feld der Psychotherapie, den internationalen Diskussionsstand zur Evidence-Based
Medicine (EBM) dar und kontrastiert diesen mit einigen zentralen Aspekten gegenwärtiger
Psychotherapieforschung. Im ersten Teil werden zunächst drei Bedeutungen von EBM unterschieden:
EBM im weiteren Sinn als regulative Idee, EBM im engeren Sinn als kodifizierte Methode
und EBM im Kontext als sozialpolitische Bewegung; anschließend werden Vor- und Nachteile
randomisiert kontrollierter Studien (RCT) diskutiert. Im zweiten Teil wird zwischen
der Binnen- und der Außenperspektive hinsichtlich EBM in der psychotherapeutischen
Medizin differenziert; danach wird kurz auf die Auseinandersetzung um Grawes Metaanalyse
und die sogenannte „Consumer Reports”-Studie sowie ausführlicher auf die Diskussion
um „Empirically Supported Treatments” eingegangen. Die Probleme der Anwendung von
RCT in der Psychotherapieforschung werden dabei ebenso dargelegt wie die derzeitigen
Vorschläge für Alternativen, die der Erforschung real praktizierter Psychotherapien
dienen.
This review article gives an overview of the state of the art of evidence-based medicine
(EBM) which is contrasted with some central aspects of current psychotherapy research.
In the first part, three meanings of EBM are discussed: EBM as a regulative idea,
EBM as a codified method and EBM as a sociopolitical movement; it follows an evaluation
of the advantages and disadvantages of randomized controlled trials (RCT). In the
second part, the discussions surrounding the metaanalysis of Grawe, the „Consumer
Reports” study and the so-called „Empirically Supported Treatments” are touched upon
briefly; it follows a discussion of the specific problems of using RCTs in psychotherapy
research and of the suggestions for more naturalistic studies in this field.
Key words
Evidence-based medicine - Psychotherapy research - Randomized controlled trial - Naturalistic
designs
Literatur
- 1
Porszolt F, Kunz R.
Unterschiede zwischen Evidence-Based Medicine und konventionell bester Medizin.
Med Klin.
1997;
92
567-569
- 2
Kerridge I, Lowe M, Henry D.
Ethics and evidence based medicine.
BMJ.
1998;
316
1151-1153
- 3 Healy D. The antidepressant era. Cambridge, Mass.; Harvard University Press 1997
- 4 Sturdee P. Evidence, influence, or evaluation? The status of scientific research
outcomes in psychiatry. Vortrag, gehalten bei „Evidence in the Balance”. Joint Conference
of Association of University Reachers of Psychiatry, Royal College of Psychiatrists
Psychotherapy Faculty, University Psychotherapy Association. Sheffield; 23. - 25.
4. 1998
- 5 Wessely S. Randomised control trials: The gold standard? Vortrag, gehalten bei Evidence
in the Balance. Sheffield; 3. - 25. 4. 1998:
- 6
Schulz K F.
Randomised trials, human nature, and reporting guidelines.
Lancet.
1996;
348
596-598
- 7
Altman D G.
Better reporting of randomised controlled trials: the CONSORT statement.
BMJ.
1996;
313
570-571
- 8
Black D.
The limitations of evidence.
J Roy Coll Physicians (London).
1998;
32
23-26
- 9
Sackett D, Wennberg J E.
Choosing the best research design for each question.
BMJ.
1997;
315
1636
- 10
Chalmers I.
Unbiased, relevant, and reliable assessments in health care.
BMJ.
1998;
317
1167-1168
- 11
Edwards S JL, Lilford R J, Hewison J.
The ethics of randomised controlled trials from the perspectives of patients, the
public, and healthcare professionals.
BMJ.
1998;
317
1209-1212
- 12
McPherson K, Chalmers I.
Incorporating patient preferences into clinical trials.
BMJ.
1998;
317
78
- 13
Torgerson D, Sibbald B.
Understanding controlled trials: What is a patient preference trial?.
BMJ.
1998;
316
360
- 14
Black N.
Why we need observational studies to evaluate the effectiveness of health care.
BMJ.
1996;
312
1215-1218
- 15
Green J, Britten N.
Qualitative research and evidence based medicine.
BMJ.
1998;
316
1230-1232
- 16
Newton J, West E.
Evidence-based medicine and compassion.
BMJ.
1996;
347
1839
- 17
Shuchman M.
Evidence-based medicine debated.
Lancet.
1996;
347
1396
- 18 McKeown T. Die Bedeutung der Medizin. Frankfurt; Suhrkamp 1982
- 19 Henningsen P. Was „leistet” die Psychosomatische Medizin im Unterschied zur naturwissenschaftlichen?
Texte und Materialien der FESt Reihe A Nr. 32. Heidelberg: FESt; 1990
- 20
Dührssen A.
Katamnestische Ergebnisse bei 1004 Patienten nach analytischer Therapie.
Z Psychosom Med. Psychoanal.
1962;
8
94-114
- 21
Widlöcher D.
Quality control, condensed analysis and ethics.
Int J Psycho-Anal.
1998;
8
1-11
- 22
Rudolf G.
Psychotherapieforschung bezogen auf die psychotherapeutische Praxis.
Psychother. Forum.
1996;
4
124-134
- 23 Margison F. Where are we now? Where are we going? Vortrag, gehalten bei „Evidence
in the Balance”. Sheffield; 23. - 25. 4. 1998
- 24
Egle U T.
Behandlung der Migräneattacke und Migräneprophylaxe: Migräne ist häufig psychosomatisch
bedingt.
Dt. Ärztebl..
1998;
95
965
- 25
Rudolf G.
Taxonomie der Psychotherapieforschung.
Psychother. Forum.
1998;
6
80-91
- 26 Grawe K, Donati R, Bernauer F. Psychotherapie im Wandel. Von der Konfession zur
Profession. Göttingen; Hogrefe 1994
- 27 Tschuschke V, Heckrath C, Tress W.
Zwischen Konfusion und Makulatur. In: Grawe, Donati, Bernauer (Hrsg) Zum Wert der Berner Psychotherapie-Studie. Göttingen;
Vandenhoeck & Ruprecht 1997
- 28 Tschuschke V.
Zu den wissenschaftlichen Fakten der Berner Metaanalyse von Grawe et al. In: Tschuschke V, Heckrath C, Tress W (Hrsg) Zwischen Konfusion und Makulatur. Zum
Wert der Ber-ner Psychotherapie-Studie von Grawe, Donati und Bernauer. Göttingen;
Vandenhoeck & Ruprecht 1997
- 29
Strauß B M, Kächele H.
The writing on the wall: Comments on the current discussion about empirically validated
treatments in Germany.
Psychother Res.
1998;
8
158-170
- 30
Elliott R.
Editor's introduction: A guide to the Empirically Supported Treatments controversy.
Psychother Res.
1998;
8
115-125
- 31
Henry W P.
Science, politics, and the politics of science: The use and misuse of empirically
validated treatment research.
Psychother Res.
1998;
8
126-140
- 32
Wampold B E.
Methodological problems in identifying efficacious psychotherapies.
Psychotherapy Res.
1997;
7
21-43
- 33
Binder J.
Observations on the training of therapists in time-limited dynamic psychotherapy.
Psychother.
1993;
30
592-598
- 34
Bohart A C, O'Hara M, Leitner L M.
Empirically violated treatments: Disenfranchisement of humanistic and other psychotherapies.
Psychother Res.
1998;
8
141-157
- 35
Crits-Christoph P, Mintz J.
Implications of therapist effects for the design and analysis of comparative studies
of psychotherapies.
J Consult Clin Psychol.
1991;
59
20-26
- 36
Jacobson N S, Christensen A.
Studying the effectiveness of psychotherapy: How well can clinical trials do the job?.
Am Psychologist .
1996;
51
1031-1039
- 37
Hollon S D.
The efficacy and effectiveness of psychotherapy relative to medications.
Am Psychologist.
1996;
51
1025-1030
- 38
Goldfried M R, Wolfe B E.
Psychotherapy practice and research: Repairing a strained alliance.
Am Psychologist.
1996;
51
1007-1016
- 39
Seligman M EP.
Science as an ally of practice.
Am Psychologist.
1996;
51
1072-1079
- 40
Krotkin M, Daviet C, Gurin J.
The Consumer Reports Mental Health Survey.
Am. Psychologist.
1996;
51
1080-1082
- 41
Howard K I, Moras K, Brill P L, Martinovich Z, Lutz W.
Evaluation of psychotherapy: Efficacy, effectiveness, and patient progress.
Am. Psychologist.
1996;
51
1059-1064
- 42
Barlow D H.
Health care policy, psychotherapy research, and the future of psychotherapy.
Am. Psychologist.
1996;
51
1050-1058
- 43
Shrout P E.
Causal modeling of epidemiological data on psychiatric disorders.
Soc. Psychiatry Psychiatr Epidemiol.
1998;
33
400-404
- 44
Fröhlich T, Haux R, Henningsen P, Miall D S, Roebruck P.
Attention based neuronal processing: A probabilistic model of non-hierarchical neuronal
convergence.
Eur J Neurosc.
1998;
10 (Suppl. 10)
405
- 45
Jacobson N S, Roberts L J, Berns S B, McGlinchey J B.
Methods for defining and determining the clinical significance of treatment effects:
description, application, and alternatives.
J Consult Clin Psychol.
1999;
67
300-307
- 46
Evans C, Margison F, Barkham M.
The contribution of reliable and clinically significant change methods to evidence-based
mental health.
Evid Based Ment Health.
1998;
1
70-72
- 47 Roth A, Fonagy P. What works for whom? A critical review of psychotherapy research. New
York; Guilford Press 1996
- 48 Parry G, Margison F. Developing evidence-based practice: where are we now? Where
are we going? Vortrag, gehalten bei Evidence in the Balance. Sheffield; 23. - 25.
4. 1998:
- 49 CORE System Group. CORE system (information management) handbook. Leeds: CORE System
Group, 1998.
- 50
Parry G.
Evidence based psychotherapy: special case or special pleading?.
Evid Based Mental Health.
2000;
3
35-37
- 51
Benson K, Hartz A J.
A comparison of observational studies and randomized, controlled trials.
New Engl J Med.
2000;
342
1878-11886
- 52
Concato J, Shah N, Horwitz R I.
Randomized, controlled trials, observational studies, and the hierarchy of research
designs.
New Engl J Med.
2000;
342
1887-1892
- 53
Pocock S J, Elbourne D R.
Randomized trials or observational tribulations?.
New Engl J Med.
2000;
342
1907-1908
Dr. med. HenningsenPeter
Psychosomatische Universitätsklinik
Thibautstr. 2
69115 Heidelberg
Email: peter_henningsen@med.uni-heidelberg.de