Neues beim Schlaganfall

Zusammenfassung

Diese Übersicht referiert die wichtigsten Publikationen zu dem Thema Schlaganfall aus der 2. Jahreshälfte 1999 bis zum Herbst 2000. Die wesentlichsten Fortschritte wurden im Bereich der Primärprävention und im Bereich der Akuttherapie erzielt.

New Publications on Stroke

This review summarizes the most important publications concerning stroke from the second half of 1999 until the second half of 2000. The most important studies were performed in the areas of primary prevention and acute therapy.

Literatur

• 1 Berges S, Moulin T, Berger E. et al . Seizures and epilepsy following strokes: recurrence factors.  Eur Neurol. 2000;  43 3-8
• 2 Berger K, Ajani U A, Kase C S. et al . Light-to-moderate alcohol consumption and the risk of stroke among U.S. male physicians.  NEJM. 1999;  341 1557-1564
• 3 Hart C L, Smith G D, Hole D J, Hawthorne V M. Alcohol consumption and mortality from all causes, coronary heart disease, and stroke: results from a prospective cohort study of Scottish men with 21 years of follow up.  BMJ. 1999;  318 1725-1729
• 4 Hillborn M, Numminnen H, Juvela S. Recent heavy drinking of alcohol and embolic stroke.  Stroke. 1999;  30 2307-2312
• 5 Rubins H B, Robins S J, Collins D. et al . Gemfibrozil for the secondary prevention of coronary heart disease in men with low levels of high-density lipoprotein cholesterol.  N EngI J Med. 1999;  341 410-418
• 6 Hess D C, Demchuk A M, Brass L M, Yatsu F M. HMG-CoA reductase inhibitors (statins). A promising approach to stroke prevention.  Neurology. 2000;  54 790-796
• 7  The Scandinavian Simvastatin Survival Study Group. Randomised trial of cholesterol lowering in 4444 patients with coronary heart disease: the Scandinavian Simvastatin Survival Study (4S).  Lancet. 1994;  344 1383-1389
• 8 Plehn J F, Davis B R, Sacks F M. et al . Reduction of stroke incidence after myocardial infarction with pravastatin - The Cholesterol and Recurrent Events (CARE) study.  Circulation. 1999;  99 216-223
• 9  The Long-Term Intervention with Pravastatin Ischemic Disease (LIPID) Study Group. Prevention of cardiovascular events and death with pravastatin in patients with coronary heart disease and a broad range of initial cholersterol levels.  N EngI J Med. 1998;  339 1349-1357
• 10 Collins R, Peto R, MacMahon S. et al . Blood pressure, stroke and coronary heart disease. Part 2, short-term reductions in blood pressure: overview of randomized drug trials in their epidemiological context.  Lancet. 1990;  335 827-838
• 11  Heart Outcomes Prevention Evaluation (HOPE) Study Investigators. Effects of ramipril on cardiovascular and microvasular outcomes in people with diabetes mellitus: results of the HOPE study and MICRO-HOPE substudy.  Lancet. 2000;  355 253-259
• 12  The Heart Outcomes Prevention Evaluation Study Investigators. Effects of an angiotensin-converting-enzyme inhibitor, ramipril, on cardiovascular events in high-risk patients.  New EngI J Med. 2000;  342 145-153
• 13  The ALLHAT Officers and Coordinators for the ALLHAT Collaborative Research Group. Major cardiovascular events in hypertensive patients randomized to doxazosin versus chlorthalidone. The antihypertensive and lipid-lowering treatment to prevent heart attack trial (ALLHAT).  JAMA. 2000;  283 1967-1975
• 14 Hart R G, Halperin J L, McBride R. et al . Aspirin for the primary prevention of stroke and other major vascular events. Meta-analysis and hypotheses.  Arch Neurol. 2000;  57 326-332
• 15 Diener H. Aspirin in the prevention of strokes.  Biomed & Pharmacother. 1999;  53 309-311
• 16 Arboix A, Oliveres M, Massons J. et al . Early differentiation of cardioembolic from atherothrombic cerebral infarction: a multivariate analysis.  European Journal of Neurology. 1999;  6 677-683
• 17 Albers G W, Bates V E, Clark W M. et al . Intravenous tissue-type plasminogen activator for treatment of acute ischemic stroke - The Standard Treatment with Alteplase to Reverse Stroke (STARS) Study.  JAMA. 2000;  283 1145-1150
• 18 Katzan I, Furlan A, Lloyd L. et al . Use of tissue-type plasminogen activator for acute ischemic stroke.  JAMA. 2000;  283 1151-1158
• 19 Clark W M, Albers G W, Madden K P, Hamilton S. for the Thrombolytic Therapy in Acute Ischemic Stroke Study Investigators . The rtPA (alteplase) 0- to 6-hour acute stroke trial, part A. Results of a double-blind, placebo-controlled, multicenter study.  Stroke. 2000;  31 811-816
• 20 Furlan A, Higashida R, Wechsler L. et al . Intra-arterial Prourokinase for acute ischemic stroke - The PROACT II Study: A randomized controlled trial.  JAMA. 1999;  282 2003-2011
• 21 Sherman D G, Atkinson R P, Chippendale T. et al . Intravenous ancrod for treatment of acute ischemic stroke. The STAT study: a randomized controlled trial.  JAMA. 2000;  283 2395-2403
• 22 Berge E, Abdelnoor M, Nakstad P H, Sandset P M. on behalf of the HAEST Study Group . Low molecular-weight heparin versus aspirin in patients with acute ischaemic stroke and atrial fibrillation: a double-blind randomised study.  Lancet. 2000;  355 1205-1210
• 23 Schwarz S, Schwab S, Steiner H-H. et al . Fibrinolyse intraventrikulärer Hämatome mit rt-PA.  Nervenarzt. 1999;  70 123-130
• 24 Roos Y. for the STAR study group . Antifibrinolytic treatment in subarachnoid hemorrhage - A randomized placebo-controlled trial.  Neurology. 2000;  54 77-82
• 25 Rothwell P M, Warlow C P. on behalf of the European Carotid Surgery Trialists, Collaborative Group . Prediction of benefit from carotid endarterectomy in individual patients: a risk-modelling study.  Lancet. 1999;  353 2105-2110
• 26  NASCET Collaborators. Benefical effect of carotid endarterectomy in symptomatic patients with high-grade carotid stenosis.  N Engl J Med. 1991;  325 505-507
• 27 Ferguson G G, Eliasziw M, Barr H WK. et al . The North American symptomatic carotid endarterectomy trial: surgical result in 1415 patients.  Stroke. 1999;  30 1751-1758
• 28 Polamäki H, Kaste M, Berg A. et al . Prevention of poststroke depression: 1 year randomised placebo controlled double blind trial of mianserin with 6 month follow up after therapy.  J Neurol Neurosurg Psychiatry. 1999;  66 490-494
• 29 Kotila M, Numminen H, Waltimo O, Kaste M. Depression after stroke - Results of the FINNSTROKE Study.  Stroke. 1998;  29 368-372
• 30 Kotila M, Numminen H, Waltimo O, Kaste M. Post-stroke depression and functional recovery in a population-based stroke register. The Finnstroke study.  Eur J Neurol. 1999;  6 309-312
• 31 Phjasvaara I, Leppävuori A, Siira I. et al . Frequency and clinical determinants of poststroke depression.  Stroke. 1998;  29 2311-2317