A New Synthesis of Enone Phosphonates

SHORTPAPER

George A. Kraus*, Prabir K. Choudhury
Department of Chemistry, Iowa State University, Ames, IA 50011, USA
e-Mail: gakraus@iastate.edu;

Abstract

Keto phosphoranes 5,6 react with phosphonate aldehyde 3 to afford enone phosphonates 1 (R = H, Me) in excellent yields.

Wittig reagent - ozonolysis - unsaturated ketones

<A NAME="RM02101SS-1">1</A> Lee SY. Lee BS. Lee C.-W. Oh DY. J. Org. Chem 2000, 65: 4175 ; and references cited therein

<A NAME="RM02101SS-2">2</A> Borowitz GB. Borowitz IJ. Handbook of Organophosphorus Chemistry Engel R. Dekker; New York: 1992. p.115-172

<A NAME="RM02101SS-3">3</A> Wolff B. Sanglier J.-J. Wang Y. Chem. Biol. 1997, 4: 139

<A NAME="RM02101SS-4">4</A> Gil JM. Hah JH. Park KY. Oh DY. Synth. Commun. 2000, 30: 789

<A NAME="RM02101SS-5">5</A> Oehler E. Kang HS. Zibral E. Synthesis 1988, 623