Literatur
- 1
De Felipe C, Herrero J F, O’Brien J A. et al .
Altered nociception,
analgesia and aggression in mice lacking the receptor for substance
P.
Nature.
1998;
392
394-397
- 2
Froger N, Gardier A M, Moratalla R. et al .
5-hydroxytryptamine (5-HT)1A autoreceptor
adaptive changes in substance P (neurokinin 1) receptor knock-out
mice mimic antidepressant-induced desensitization.
J Neurosci.
2001;
21
8188-8197
- 3
Kramer M S, Cutler N, Feighner J. et al .
Distinct mechanism for antidepressant activity
by blockade of central substance P receptors.
Science.
1998;
281
1640-1645
- 4
Lieb K, Ahlvers K, Dancker K. et
al .
Effects of the neuropeptide substance P on sleep,
mood, and neuroendocrine measures in healthy young man.
Neuropsychopharmacology.
2002;
(in press)
- 5
Lieb K, Treffurth Y, Fiebich B L, Berger M.
Substance P and affective
disorders: New treatment opportunities by Neurokinin 1 Receptor
Antagonists?.
Neuropsychobiology.
2002;
45
(Suppl 1)
2-6
- 6
Otsuka M, Yoshioka K.
Neurotransmitter functions
of mammalian tachykinins.
Physiological Reviews.
1993;
73
229-308
- 7
Quartara L, Maggi C A.
The tachykinin
NK1 receptor. Part II: Distribution and pathophysiological roles.
Neuropeptides.
1998;
32
1-49
- 8
Rupniak N M.
Elucidating
the antidepressant actions of substance P (NK1 receptor) antagonists.
Curr
Opin Investig Drugs.
2002;
3
257-261
- 9
Rupniak N M, Kramer M S.
Discovery of
the antidepressant and anti-emetic efficacy of substance P receptor
(NK1) antagonists.
Trends Pharmacol Sci.
1999;
20
485-490
- 10
Santarelli L, Gobbi G, Debs P C. et al .
Genetic and pharmacological disruption
of neurokinin 1 receptor function decreases anxiety-related behaviors
and increases serotonergic function.
Proc Natl Acad Sci
USA.
2001;
98
1912-1917
Priv.-Doz. Dr. med. Klaus Lieb
Universitätsklinikum Freiburg, Abteilung für
Psychiatrie und Psychotherapie
Hauptstraße 5
79104 Freiburg
Phone: 0761/2706681
Fax: 0761/2706667
Email: klaus_lieb@psyallg.ukl.uni-freiburg.de
