Zusammenfassung
Der Thunderclap headache ist ein explosionsartig auftretender Kopfschmerz heftigster
Intensität. Obwohl für den Patienten ein dramatisches Ereignis, muss er nicht unbedingt
Symptom einer gefährlichen Erkrankung sein. Ziel dieser Übersichtsarbeit ist es, mit
dem Thunderclap headache als eigenständige Kopfschmerzerkrankung vertraut zu machen
sowie die Differenzialdiagnosen einschließlich deren diagnostischer Evaluierung darzustellen.
Neben dem symptomatischen/sekundären Thunderclap headache gibt es auch eine benigne/primäre
Form. Beide Formen können weder in ihrer klinischen Präsentation noch aufgrund anamnestischer
Angaben unterschieden werden. Jeder plötzlich auftretende, sehr starke Kopfschmerz
muss als potenziell gefährlich angesehen werden und erfordert eine prompt durchzuführende
und gründliche Zusatzdiagnostik bevor die Diagnose eines primären Thunderclap headache
gestellt werden darf. Zerebrale Computertomographie und gegebenenfalls Liquorpunktion
sind zum Ausschluss einer Subarachnoidalblutung obligat. Zur Abklärung weiterer möglicher
Ursachen sollte eine Kernspintomographie des Gehirns einschließlich MR-Angiographie
durchgeführt werden. Gegebenenfalls sind auch andere spezielle Untersuchungen notwendig.
Abstract
Thunderclap haeadche is an explosive very severe headache. Although a dramatic event
for the patient, it is not necessarily symptom of a dangerous disease. The aim of
this review is to address the syndrome of primary thunderclap headache, the differential
diagnoses and appropriate diagnostic evaluation. In addition to symptomatic/secondary
thunderclap headache a benign/primary thunderclap headache exists. Symptomatic and
benign thunderclap headache cannot be distinguished clinically. Every severe sudden
headache has to be considered as potentially dangerous and requires prompt and thourough
diagnostic evaluation before a primary thunderclap headache can be diagnosed. To exclude
subarachnoid hemorrhage, brain computed tomography, and if negative, lumbar puncture
are obligatory. MRI and MR angiography should be performed to rule out other symptomatic
forms of thunderclap headache. In some cases it is necessary to perform additional
specific examinations.
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Prof. Dr. Hans-Christoph Diener,F. A. H. A.
Neurologische Universitätsklinik Essen
Hufelandstraße 55
45122 Essen
Email: h.diener@uni-essen.de