ABSTRACT
Pulmonary embolism (PE) and deep venous thrombosis (DVT) remain major problems in
medicine that receive less attention from healthcare professionals and the public
than either coronary artery disease or acute myocardial infarction. Furthermore, strategies
proven to minimize the frequency of PE and DVT are not widely employed on a consistent
and effective basis. The problem is widespread and affects patients in acute care
hospitals, rehabilitation hospitals, and skilled nursing facilities, as well as high-risk
individuals at home. Internists, general practitioners, and family doctors confront
the greatest challenges in implementing appropriate prophylaxis. Models for effective
change exist in cardiovascular and surgical practices where the imperative for prevention
of further disease is insisted upon and ingrained in the culture of clinicians.
We will review the epidemiology of venous thromboembolism, strategies for the primary
and secondary prevention of PE and DVT, “real world” use of prophylaxis, barriers
to change that exist in the “real world,” and initiatives to improve day-to-day practice.
We will conclude by posing 10 questions for future research on this topic.
KEYWORDS
Deep venous thrombosis - prophylaxis - venous thromboembolism - risk