Small preterm infants usually require a heated environment to survive. After weaning,
some infants become hypothermic, and eventually require external thermal support for
an additional period. We hypothesized that preterm infants respond to weaning from
an incubator by increasing their resting metabolic rate. Thermally stable infants
were studied when they had reached a weight of at least 1600 g. Resting energy expenditure
was measured 2 hours before weaning and at 6, 23, 30, and 53 hours after weaning.
Two-way analysis of variance for repeated measures was used for analysis. Sixteen
infants with mean birthweight of 1270 ± 375 g and gestational age 31 ± 2.3 weeks were
studied. After weaning, there was a significant increase in energy expenditure from
95.0 ± 21.9 kcal/d in the incubator, to a 30-hours peak of 111.9 ± 10.5 kcal/d after
weaning. Weaning from a convective incubator results in an increase in metabolic rate
in very low birth weight infants. We speculate that the infants' ability to increase
metabolic rate might influence weaning success.
KEYWORDS
Preterm infants - energy metabolism - oxygen consumption
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Shaul DollbergM.D.
Department of Neonatology, Lis Maternity Hospital, Tel Aviv-Sourasky Medical Center
6 Weizman Street
Tel Aviv 64239, Israel