Planta Med 2005; 71(10): 960-961
DOI: 10.1055/s-2005-864179
Letter
© Georg Thieme Verlag KG Stuttgart · New York

New Acylated Clionasterol Glycosides from Valeriana officinalis

Srinivas V. Pullela1 , Young Whan Choi1 , Shabana I. Khan1 , Ikhlas A. Khan1 , 2
  • 1National Center for Natural Products Research, Research Institute of Pharmaceutical Sciences, The University of Mississippi, University, MS, USA
  • 2Department of Pharmacognosy, School of Pharmacy, The University of Mississippi, University, MS, USA
Further Information

Publication History

Received: January 4, 2005

Accepted: March 4, 2005

Publication Date:
19 August 2005 (online)

Abstract

The chloroform extract of Valeriana officinalis led to the isolation of clionasterol-3-O-β-D-glucopyranoside and a mixture of 6′-O-acyl-β-D-glucosyl-clionasterols. The acyl moieties were identified as hexadecanoyl, 8E,11E-octadecadienoyl and 14-methylpentadecanoyl by alkaline hydrolysis followed by GC-MS analysis. The isolated compounds did not exhibit any anti-inflammatory, anticancer or cytotoxic activity when tested in a variety of in vitro cell-based assays.

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Dr. Ikhlas A. Khan

National Center for Natural Product Research

The University of Mississippi

University

MS 38677

USA

Fax: +1-662-915-7989

Email: ikhan@olemiss.edu

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