Zusammenfassung
Offizielle Therapieempfehlungen zur Therapie akuter Manien gibt es sowohl auf nationaler
als auch auf internationaler Ebene. Sie werden auf der Basis der wissenschaftlichen
Evidenz von einer Expertenkommission für die jeweiligen Psychopharmaka oder Therapiestrategien
erstellt und in eine in der klinischen Praxis einsetzbare Form gebracht. Die World
Federation of Societies of Biological Psychiatry (WFSBP) hat im Jahre 2003 solche
Therapieempfehlungen publiziert. Sie geben einen Überblick über die relevanten Psychopharmakastudien
zur akuten Manietherapie und zeigen einen Algorithmus auf, der sich an der Schwere
der manischen Episode orientiert. Dabei gibt es vier Evidenzkategorien (A - D), die
Auskunft über die Qualität der vorhandenen Studien geben.
Abstract
There are several national and international practice guidelines on the treatment
of acute mania. Their purpose is to assess the available evidence of efficacy for
medication used in the treatment of bipolar mania and to grade it according to the
quality of studies available. The World Federation of Societies of Biological Psychiatry
(WFSBP) has developed such guidelines in 2003. They categorize the scientific quality
of the studies into four levels of evidence (A - D) and provide an algorithm based
on the degree of severity of the acute manic episode.
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Dr. med. Heinz Grunze
Klinik und Poliklinik für Psychiatrie der Ludwig-Maximilians-Universität München
Nußbaumstraße 7
80336 München
eMail: heinz.grunze@med.uni-muenchen.de
