ABSTRACT
Depression after stroke is common. Although different opinions exist about the definition,
diagnosis, and measurement of outcomes related to depression after stroke, there is
little debate about the prevalence of depression symptoms and their impact on stroke
survivors and their families. Depression after stroke has long been recognized as
a common condition with many negative effects in the poststroke period, but more recently
depression has also been identified as an independent stroke risk factor. Given that
there are at least 500,000 new ischemic strokes yearly in the United States, a conservative
estimate is that 150,000 U.S. stroke survivors develop poststroke depression each
year. Because effective treatments exist but are likely underutilized for depression,
this is an important example of an evidence-practice gap to which increased efforts
to improve care should be made. Such efforts would likely improve not only patient
symptoms but may also decrease stroke risk, influence stroke functional recovery,
decrease mortality, and reduce poststroke health care utilization. This article provides
an overview of depression diagnosis in stroke, reviews the epidemiology of poststroke
depression and its associated morbidity and mortality, and reviews existing evidence
on the treatment and prevention of poststroke depression.
KEYWORDS
Stroke - depression - recovery - risk factors
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