Palladium on Activated Carbon - A Recyclable Catalyst for Suzuki-Miyaura Cross-Coupling of Aryl Chlorides in Water

Morten Lysén; Klaus Köhler

doi:10.1055/s-2006-926305

PAPER

Palladium on Activated Carbon - A Recyclable Catalyst for Suzuki-Miyaura Cross-Coupling of Aryl Chlorides in Water

Morten Lysén*^a,b, Klaus Köhler^a
^a Department Chemie, Anorganische Chemie, TU München, Lichtenbergstr. 4, 85747 Garching, Germany
^b The Danish University of Pharmaceutical Sciences, Universitetsparken 2, 2100 Copenhagen, Denmark
Fax: +4535306040; e-Mail: mly@dfuni.dk;

Abstract

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Abstract

Aryl chlorides are efficiently coupled with aryl boronic acids using ligandless Pd/C in water. The catalyst is easily recovered via filtration and reused up to four times with an overall yield of 73%. In addition the catalytic activity and selectivity of a variety of homogeneous and heterogeneous palladium sources have been compared.

Key words

aryl chlorides - water - palladium - cross-coupling - biaryls

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