Abstract
Dihydroisoquinoline derivatives and their analogues, prepared by the Bischler-Napieralsky
reaction, were converted to their indole-fused derivatives. Scope and limitations
of the palladium-catalyzed reaction, proceeding through the tautomeric enamine forms
of these compounds, were studied and the process was extended to the preparation of
racemic mangochinine.
Key words
ring closure - palladium - catalysis - indoles - natural products
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