Zusammenfassung
Auf dem jährlichen Treffen der „Association for Research in Vision and Ophthalmology”
(ARVO) 2005 wurden neueste Forschungsergebnisse aus sämtlichen ophthalmologischen
Disziplinen vorgestellt. Von besonderem Interesse war der aktuelle Forschungsstand
in den Bereichen „trockenes Auge” und „okuläre Allergie”. Da diese beiden Erkrankungen
häufig und aufgrund einer Reihe sich überschneidender Symptome oft schwer zu differenzieren
sind, besteht Bedarf an schnelleren und genaueren Diagnosemethoden. Daher wurden zahlreiche
neue Hilfsmittel vorgestellt, die in klinischen Studien, aber auch in der täglichen
klinischen Praxis die Differenzialdiagnose zwischen trockenem Auge und okulärer Allergie
erleichtern. Ein besseres Verständnis der molekularen Mechanismen in der Pathogenese
dieser Krankheitsprozesse hat zudem zu neuen Behandlungsstrategien beim trockenen
Auge und der okulären Allergie geführt.
Abstract
The 77th meeting of the Association for Research in Vision and Ophthalmology (ARVO) presented
the latest developments in clinical research and practice across a range of ophthalmic
disciplines. Of particular interest was the current status of research in dry eye
and ocular allergy. With these conditions being very common to ophthalmologists, and
the fact that they are difficult to differentiate due to the number of overlapping
symptoms, there remains a need for more rapid and accurate methods for their diagnosis.
Therefore, a number of new tools were presented that have the potential for use in
clinical trials and practice to improve the diagnosis and assessment of dry eye and
ocular allergy. Some of these tools have been developed based on a greater understanding
of the pathophysiology of dry eye and ocular allergy, and the various molecular pathways
involved. Indeed, a greater understanding of the molecular mechanisms involved in
the pathogenesis of dry eye and ocular allergy has identified potential targets for
the treatment of these conditions. Continuing research into new agents can provide
ophthalmologists with a number of options that will ultimately benefit the patient.
Schlüsselwörter
Trockenes Auge - okuläre Allergie
Key words
Dry eye syndrome - ocular allergy
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Dr. Elisabeth M. Messmer
Augenklinik der Ludwig-Maximilians-Universität
Mathildenstr. 8
80336 München
Telefon: ++49/89/51 60 38 11
Fax: ++49/89/51 60 51 60
eMail: emessmer@med.uni-muenchen.de