Identifizierung von Tumorantigenen: Strategien und Perspektiven

Tumorantigen - Immuntherapie - tumorspezifische Immunantwort

tumor antigen - immuntherapy - tumor-specific immune response

Literatur

• 1 Jäger D, Taverna C, Zippelius A, Knuth A. Identification of tumor antigens as potential target antigens for immunotherapy by serological expression cloning.  Cancer Immunol Immunother. 2004;  53 144-147
• 2 Boon T, Coulie P G, Van den Eynde B. Tumor antigens recognized by T cells.  Immunology Today. 1997;  18 267-268
• 3 Simpson A JG, Caballero O L, Jungbluth A, Chen Y T, Old L J. Cancer/testis antigens, gametogenesis and cancer.  Nat Rev Cancer. 2005;  5 615-625
• 4 Jäger E, Jager D, Knuth A. Antigen-specific immunotherapy and cancer vaccines.  Int J Cancer. 2003;  160 817-820
• 5 Zippelius A, Batard P, Rubio-Godoy V. et al . Effector function of human tumor-specific CD8 T cells in melanoma lesions: a state of local functional tolerance.  Cancer Res. 2004;  64 2865-2873