Original Approach to New Derivatives of [1,3]Oxazolo[4,5-d]pyrimidine

Vitaliy M. Sviripa; Andrei A. Gakh; Vladimir S. Brovarets; Aleksei V. Gutov; Boris S. Drach

doi:10.1055/s-2006-950221

PAPER

Original Approach to New Derivatives of [1,3]Oxazolo[4,5-d]pyrimidine

Vitaliy M. Sviripa^a, Andrei A. Gakh^b, Vladimir S. Brovarets^a, Aleksei V. Gutov^c, Boris S. Drach*^a
^a Institute of Bioorganic Chemistry and Petrochemistry, National Academy of Sciences of Ukraine, Murmanskaya str. 1, 02094 Kyiv, Ukraine
Fax: +380(44)5732561; e-Mail: drach@bpci.kiev.ua;
^b Oak Ridge National Laboratory Washington, P.O. Box 2008, Oak Ridge, TN 37381-6242, USA
^c Institute of Organic Chemistry, National Academy of Sciences of Ukraine, Murmanskaya str. 5, 02094 Kyiv, Ukraine

Abstract

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Abstract

Based on the readily available 4-dichloromethylene-2-phenyl-1,3-oxazol-5(4H)-one, preparative methods for the synthesis of a set of functionalized derivatives of the poorly studied [1,3]oxazolo[4,5-d]pyrimidine system were elaborated.

Key words

heterocycles - fused-ring systems - cyclizations - oxazoles - pyrimidines

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References

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