Planta Medica, Table of Contents Planta Med 1997; 63(1): 55-57DOI: 10.1055/s-2006-957604 PapersNatural Product Chemistry© Georg Thieme Verlag Stuttgart · New YorkChemical Constituents of Isatis indigotica Xiaoyun Wu1 , Yunhai Liu2 , Wanyun Sheng3 , Jie Sun4 , Guowei Qin1 1Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 200031, China 2Tongji Affiliated Hospital, Tongji Medical University, Wuhan 430030, China 3Shanghai Institute of Planned Parenthood Research, Shanghai 200032, China 4Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, Shanghai 200032, China Recommend Article Abstract PDF Download Buy Article Abstract From the roots of Isatis indigotica, ten compounds (1-10) were isolated. Compound 1 is a new alkaloid whose structure was elucidated as (E)-3-(3′,5′-dimethoxy-4′-hydroxy-benzylidene)-2-indolinone. Compounds 2-4 were discovered for the first time from a natural source and compounds 5-7 were originally isolated from this species. In a preliminary study, compounds 4-8 showed antiendotoxic activities in vitro. Key words Isatis indigotica - Cruciferae - (E)-3-(3′,5′-dimethoxy-4′-hydroxybenzylidene)-2-indolinone - antiendotoxic activity PDF (287 kb)
