Molluscicidal Activity of Naphthylisoquinoline Alkaloids from Triphyophyllum and Ancistrocladus Species*

Gerhard Bringmann; Jörg Holenz; Laurent Aké Assi; Canxi Zhao; Kurt Hostettmann

doi:10.1055/s-2006-957970

Planta Medica, Table of Contents

Planta Med 1996; 62(6): 556-557
DOI: 10.1055/s-2006-957970

Letters

Molluscicidal Activity of Naphthylisoquinoline Alkaloids from Triphyophyllum and Ancistrocladus Species*

Gerhard Bringmann¹ , Jörg Holenz¹ , Laurent Aké Assi² , Canxi Zhao³ , Kurt Hostettmann⁴ ^, ⁵

¹Institut für Organische Chemie, Universität Würzburg, Am Hubland, D-97074 Würzburg, Germany
²Centre National de Floristique, Université d'Abidjan, 08 B.P. 172, Abidjan 08, Ivory Coast
³Hainan Provincial Hospital, Xiuying District, 570311 Haikou, Hainan Province, People's Republic of China
⁴Institut de Pharmacognosie et Phytochimie, École de Pharmacie, Université de Lausanne, BEP, CH-1015 Lausanne, Switzerland

* Part 78 in the series “Acetogenic Isoquinoline Alkaloids”. For Part 77, see ref. (1)

Abstract

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Abstract

The naphthylisoquinoline alkaloids dioncophylline A (1) and 5′-O-demethyl-8-O-methyl-7-epi-dioncophylline A (2) represent a new structural type of molluscicidal compounds and the active principle of extracts of the tropical lianas Ancistrocladus abbreviates and Triphyophyllum peltatum. The activity of 1 was further improved by derivatization.

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