Conversion of Glycals to 1-Azido-2-iodo Sugars Using N-Iodosuccinimide/Sodium­ Azide or Potassium Iodide/Oxone Reagent Systems: Application in the Synthesis of Methyl N-Acetyl-α-d-lividosaminide

Abstract

Glycals are readily converted into the corresponding 2-deoxy-2-iodoglycosyl azides, in good to excellent yields in a short time, upon treatment with N-iodosuccinimide/sodium azide or potassium iodide/Oxone reagent systems. One of these 1-azido-2-iodo sugars was converted into methyl N-acetyl-α-d-lividosaminide.

glycals - N-iodosuccinimide - sodium azide - potassium iodide - Oxone - 1-azido-2-iodo sugar - methyl N-acetyl-α-d-livido­s­aminide

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