Anti-Allergic Action of Resveratrol and Related Hydroxystilbenes

Ho Cheong; Shi-Yong Ryu; Kyeong-Man Kim

doi:10.1055/s-2006-960773

Planta Medica, Table of Contents

Planta Med 1999; 65(3): 266-268
DOI: 10.1055/s-2006-960773

Letter

Anti-Allergic Action of Resveratrol and Related Hydroxystilbenes

Ho Cheong¹ , Shi-Yong Ryu² , Kyeong-Man Kim¹

¹Pharmacology Laboratory, College of Pharmacy, Chonnam National University, Kwang-Ju, Korea
²Korea Research Institute of Chemical Technology, Taejeon, Korea

Abstract

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Abstract

Resveratrol (1) and nine related hydroxystilbene compounds (2 ∼ 9) isolated from plants were evaluated for the anti-allergic activities in vitro. Resveratrol (1) and rhapontigenin (5) demonstrated significant inhibitions upon the release of β-hexosaminidase from the cultured RBL-2H3 cells in a dose-dependent manner and the IC₅₀ values were calculated as 14 and 15 µM, respectively.

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