Tricyclic Diterpenes from the Stem Bark of Azadirachta indica

Abstract

Two new diterpenoids, margosone and margosolone, have been isolated from the stem bark of Azadirachta indica A. Juss (neem) and their structures established as 12,13-dihydroxy-14-isoporpylpodocarpa-8,11,13-trien-7-one and 13-hydroxy-12-methoxypodocarpa-8,11,13-trien-7-one, respectively, through chemical and spectroscopic studies.

Azadirachta indica - Meliaceae - stem bark - diterpenoids