Armillaric Acid, A New Antibiotic Produced by Armillaria mellea

Tadashi Obuchi; Hideaki Kondoh; Naoharu Watanabe; Masaharu Tamai; Sadafumi Imura; Yang Jun-Shan; Liang Xiao-Tian

doi:10.1055/s-2006-960925

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Planta Med 1990; 56(2): 198-201
DOI: 10.1055/s-2006-960925

Papers

Armillaric Acid, A New Antibiotic Produced by Armillaria mellea

Tadashi Obuchi¹ , Hideaki Kondoh¹ , Naoharu Watanabe¹ , Masaharu Tamai¹ , Sadafumi Imura¹ , Yang Jun-Shan² , Liang Xiao-Tian²

¹Research Center, Taisho Pharmaceutical Co., Ltd., 1-403 Yoshino-cho, Omiya, Saitama 330, Japan
²Institute of Materia Medica, Chinese Academy of Medical Sciences, 1 Xian Nong Tan Street, Beijing, People's Republic of China

Further Information

Publication History

1989

Publication Date:
05 January 2007 (online)

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Abstract

A new antibiotic armillaric acid (2), has been isolated from the cultured mycelia of Armillaria mella (Vahl. ex Fr.) Quel (Trichlometaceae). Its structure was elucidated on the basis of the spectral data. Compound 2 exhibits inhibitory activity against gram-positive bacteria and yeast.

Key words

Armillaric acid - Armillaria mellea - Mi Huan Jun - antibiotic - NMR