Immunosuppressive Principles of Rehmannia glutinosa var. hueichingensis1

Hiroshi Sasaki; Hiroaki Nishimura; Takashi Morota; Masao Chin; Hiroshi Mitsuhashi; Yasuhiro Komatsu; Hirofumi Maruyama; Tu Guo-rui; He Wei; Xiong Yu-lang

doi:10.1055/s-2006-962064

Planta Med 1989; 55(5): 458-462
DOI: 10.1055/s-2006-962064

Papers

Immunosuppressive Principles of Rehmannia glutinosa var. hueichingensis ¹

Hiroshi Sasaki² , Hiroaki Nishimura² , Takashi Morota² , Masao Chin² , Hiroshi Mitsuhashi² , Yasuhiro Komatsu³ , Hirofumi Maruyama³ , Tu Guo-rui⁴ , He Wei⁴ , Xiong Yu-lang⁴

²Tsumura Laboratory, 3586 Yoshiwara, Ami-machi, Inashiki-gun, Ibaraki 300-11, Japan
³Tsumura Research Institute for Pharmacology, 3586 Yoshiwara, Amimachi, Inashiki-gun, Ibaraki 300-11, Japan
⁴Institute of Chinese Materia Medica, Academy of Traditional Chinese Madicine, Beixincang, Dongzhimen, Beijing, Peoples' Republic of China

1 Chemical and Biological Studies on Rehmanniae Radix; Part 1

Abstract

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Abstract

Separation of the immunosuppressive principles from Rehmanniae radix was done by monitoring hemolytic plaque-forming cells (HPFC) inhibitory activity to give two new phenethyl alcohol glycosides: jionosides A₁ (4) and B₁ (5), along with six known compounds: acetoside, isoacteoside, purpureaside C, echinacoside, and cistanosides A and F.

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Immunosuppressive Principles of Rehmannia glutinosa var. hueichingensis 1

Immunosuppressive Principles of Rehmannia glutinosa var. hueichingensis ¹