Abstract
The coexistence of esophageal submucosal tumor and carcinoma has been reported only
in very few cases up to now, and the relationship between them is unclear. To elucidate
the incidence and the pathogenesis of their coexistence, endoscopy and endoscopic
ultrasonography (EUS) were sequentially performed in 95 patients who were suspected
of having a submucosal tumor of the esophagus. EUS revealed 83 submucosal tumors and
12 cases of extraluminal compression. Two cases of esophageal carcinoma were observed
in the series. In one patient, intraepithelial carcinoma was present on a leiomyoma
originating in the muscularis mucosae, and in the other patient, multiple superficial
carcinomas were pres-
