Summary
The hypothalamus-pituitary-thyroid function was studied in 15 male patients on chronic
methadone treatment (40 mg/day).
No significant variations of TSH, T4, T3 and rT3 levels were documented, either in basal conditions or after TRH stimulation; however
a reduced TSH pituitary response was recorded in some patients (6 out of 15).
Key-Words:
TSH
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Thyroid Hormones
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TRH
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Opioid System
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Methadone
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Drug-Addicts