The effects of ventromedial hypothalamic (VMH) lesions on the circadian periodicity
of serum insulin, glucose, triglyceride and food intake were studied in rats. The
rhythms of serum insulin, glucose and triglyceride did not persist in VMH lesioned
rats. The glucose level during the light period was reduced. The triglyceride and
insulin levels were elevated. The VMH lesions markedly increased food intake during
the later half part of the light cycle but kept it significantly less during the first
half part. Thus, the VMH lesions abolished the circadian rhythmicity of serum insulin,
glucose and triglyceride and attenuated the rhythmicity of eating through increase
in daytime consumption.
Ventromedial Hypothalamic Lesions
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Circadian Rhythm
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Insulin
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Glucose
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Triglyceride
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Food Intake
