Abstract
In 1985, we were in charge of the femininity control tests for the participants of
the XXth Universiade in Kobe. At that time, we chose as screening tests checking both
X chromatin from buccal mucous membrane and Y chromatin from hair roots. The number
of female competitors who attended the Universiade, except tennis, gymnastics, and
fencing, was 631. Among them, 108 had already had the certificate of femininity so
we examined 523 female competitors. All but three of them were normal for femininity,
i. e., X chromatin positive and Y chromatin negative. Two of the three exceptions
were Y chromatin positive and X chromatin negative. Chromosomal analyses from their
peripheral lymphocytes showed a pattern concordant with a 46,XY karyotype. The other
was both X and Y chromatin positive, but we could find Y chromatin on only one slide
out of three. Since this person refused to have a blood sample taken, we can only
suppose her karyotype as being 46,XX/46,XY or 46,XX/47,XXY. This last case would not
have been found, if we had checked only the X chromatin. From our experience, we conclude
that for femininity control, it is saferto screen the Y chromatin. We would strongly
advise the use of both X and Y chromatin tests for femininity control.
Key words
X chromatin - Y chromatin - femininity control - Universiade - testicular feminization
syndrome
