Cussonosides A and B, two Triterpene-saponins from Cussonia barteri

M. A. Dubois; M. Ilyas; H. Wagner

doi:10.1055/s-2007-969084

Planta Medica, Inhaltsverzeichnis

Planta Med 1986; 52(2): 80-83
DOI: 10.1055/s-2007-969084

Full Papers

Cussonosides A and B, two Triterpene-saponins from Cussonia barteri

M. A. Dubois¹ , M. Ilyas² , H. Wagner³

¹Laboratoire de Pharmacognosie, Faculté de Pharmacie, 7, Bd. Jeanne D'Arc, F-21033 Dijon Cedex, France
²Department of Pharmaceutical and Medicinal Chemistry, Ahmadu Bello University, Zaria, Nigeria
³Institut für Pharmazeutische Biologie der Universität München, Karlstr. 29, D-8000 München 2, Federal Republic of Germany

Abstract

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Abstract

Two major saponins have been isolated from the stem bark of Cussonia barteri Seem (Araliaceae). Structural elucidation employing mainly ¹H- and ¹³C-NMR, FAB-MS and GC-MS spectroscopic methods revealed a new hederagenin 28-O-[α-L-rhamnopyranosyl (1 → 4)-β-D-glucopyranosyl (1 → 6)]-β-D-glucopyranosyl ester (Cussonoside A), and the corresponding oleanolic acid analogue (Cussonoside B). Cussonoside A exhibits a pronounced sedative effect.

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