Abstract
Neuropsychopharmacological studies have been conducted on the chloroform fraction
extracted from the seeds of Syzygium cuminii L., on experimental animals. The extract was found to produce alteration in general
behaviour pattern, reduction in spontaneous motility, hypothermia, potentiation of
pentobaritone hypnosis, analgesia, reduction in exploratory behavoiur pattern, muscle
relaxant action, and suppression of aggressive behavoiur. The extract also caused
suppression of conditioned avoidance response and showed antagonism to amphetamine
group toxicity. These observations suggest that the extract of the seeds of S. cuminii possesses a potent CNS depressant action.
