Abstract
It is well known that liver tyrosine aminotransferase activity is induced by administration
of steroids to adrenalectomized rats. When various soyasaponins (e.g. soyasaponins
I, II, III, A1 and A2) were injected intraperitoneally into adrenalectomized rats, liver tyrosine aminotransferase
activity was not found to be induced. Administration of a low dose of cortisone (2.5
mg/kg body weight) to adrenalectomized rats also failed to induce liver tyrosine aminotransferase.
However, this enzyme was found to be induced by administration of this low dose of
cortisone with soyasaponins II (2.5 mg/kg and 5.0 mg/kg) and A2 (5.0 mg/kg).
