Active Principles of the Euphorbiaceae. VII. Milliamines H and I, Peptide Esters of 20-Deoxy-5ζ-Hydroxyphorbol from Euphorbia milii

A. Marston; E. Hecker

doi:10.1055/s-2007-969720

Planta Medica, Inhaltsverzeichnis

Planta Med 1984; 50(4): 319-322
DOI: 10.1055/s-2007-969720

Research Articles

Active Principles of the Euphorbiaceae. VII[1]. Milliamines H and I, Peptide Esters of 20-Deoxy-5ζ-Hydroxyphorbol from Euphorbia milii

A. Marston, E. Hecker

Instilut für Biochemie, Deutsches Krebsforschungszentrum, Im Neuenheimer Feld 280, D-6900 Heidelberg

Abstract

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Abstract

Two diesters of the new diterpene alcohol 20-deoxy-5ζ-hydroxyphorbol, milliamines H and I, have been isolated from Euphorbia milii. Both carry an acelate group in position 13. In position 12, milliamine H contains a 2-[2-(methylamino)benzoyl]aminobenzoyl dipeplide moiely and milliamine I a 2-(2-hydroxybenzoyl)aminobenzoyl moiety. They exhibil weak (H) or virtually no (I) irritant activities.

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Referenzen

1 VI^th communication, see loc. cit. (5)