DMW - Deutsche Medizinische Wochenschrift, Table of Contents Dtsch Med Wochenschr 2007; 132(18): 991-994DOI: 10.1055/s-2007-979368 Prinzip & Perspektive | Review articleGrundlagenforschung, Immunologie, Infektiologie© Georg Thieme Verlag KG Stuttgart · New YorkAllergie und ParasitenAllergies and parasitesD. Voehringer1 1Institut für Immunologie, Ludwig-Maximilians Universität München Recommend Article Abstract Buy Article(opens in new window) Schlüsselwörter Allergie - Typ 2 Immunität - Helminthparasiten - Regulatorische T-Zellen - Alternativ aktivierte Makrophagen Key words allergy - type 2 immunity - helminth parasites - regulatory T cells - alternatively activated macrophages Full Text References Literatur 1 Bach J F. The effect of infections on susceptibility to autoimmune and allergic diseases. N Engl J Med. 2002; 347 911-920 2 Brockschnieder D, Lappe-Siefke C, Goebbels S. et al . Cell depletion due to diphtheria toxin fragment A after Cre-mediated recombination. Mol Cell Biol. 2004; 24 7636-7642 3 Elston D M. The hygiene hypothesis and atopy: bring back the parasites?. J Am Acad Dermatol. 2006; 54 172-179 4 Humbles A A, Loyd C M, McMillan S J. et al . A critical role for eosinophils in allergic airways remodeling. Science. 2004; 305 1776-1779 5 Lee J J, Dimina D, Macias M P. et al . Defining a link with asthma in mice congenitally deficient in eosinophils. Science. 2004; 305 1773-1776 6 Maizels R M, Yazdanbakhsh M. Immune regulation by helminth parasites: cellular and molecular mechanisms. Nat Rev Immunol. 2003; 3 733-744 7 Mohrs M, Shinkai K, Mohrs K, Locksley R M. Analysis of type 2 immunity in vivo with a bicistronic IL-4 reporter. Immunity. 2001; 15 303-311 8 Summers R W, Elliott D E, Urban J F, Thompson R, Weinstock J V. Trichuris suis therapy in Crohn’s disease. Gut. 2005; 54 87-90 9 Voehringer D, Shinkai K, Locklsey R M. Type 2 immunity reflects orchestrated recruitment of cells committed to IL-4 production. Immunity. 2004; 20 267-277 Dr. rer. nat. David Vöhringer Institut für Immunologie, Ludwig-Maximilians Universität München Goethestraße 31 80336 München Phone: 089/218075646 Fax: 089/51602236 Email: david.voehringer@med.uni-muenchen.de