Abstract
The object of this study was to investigate correlations between lipid peroxide (MDA)
and glutathione (GSH) levels in liver, kidney, heart and brain of guinea pigs during
fasting (24 h, 48 h, 120 h) and respectively by supplementation (A single dose, 500
mg/kg bw, ip) of vitamin C (AA, Ascorbic acid) on fasting (24 h, 48 h, 120 h). MDA
and GSH levels of various tissues by fasting and AA supplemented fasting were dependent
on the function of each tissue during the fasting period. Lipid peroxide (LP) levels
of kidney, heart and brain decreased for the AA supplemented fasting period. However,
LP levels of liver increased in the AA supplemented 48 h and 120 h fasting groups.
GSH levels of all tissues were affected differently in all of the AA supplemented
fasting periods.
Key words
Lipid Peroxide - Glutathione - Fasting - Vitamin C
