ABSTRACT
The evaluation of patients with rapidly progressive dementia can be challenging, largely
due to the rarity of the conditions responsible for such fulminant presentations of
dementia. This article presents a framework for categorizing such disorders based
on the underlying pathophysiology, including degenerative, inflammatory, vascular,
toxic, metabolic, neoplastic, and infectious causes of rapidly progressive dementia.
Diagnostic approaches, representative imaging abnormalities, and treatment options
for these uncommon conditions are also presented.
KEYWORDS
Rapidly progressive dementia
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