Aims: The purpose of this study was to be included pre-postmenopausal women with abnormal
bleeding to examined by TVS measurement of endometrial thickness and diagnosis of
endometrial cytology and pathology by means of Endometrial sampling, Dilation and
Curettage, Total Abdomen Hysterectomy.
Methods: Endogyn endometrial cell sampler from 357 pre-postmenopausal women with abnormal
bleeding, 91D&Cs and 73 TAH. All the women examined by TVS and done measurement of
endometrial thickness.
Results: No Cancer: Cytology 60%, histology 54%, D&C 57%,TAH 52%. Atrophic: Cytology 16%,
histology12%,D&C 8%,TAH 17%. Hyperplasia without atypia: Cytology 8%, histology 10%,
D&C 9%, TAH 10%. Hyperplasia or polyps: Cytology 3%. Endometrial polyps: Cytology
2%,histology 11%,D&C 13%,TAH 9%.Atypical hyperplasia: Cytology 2%, histology 3%, D&C
2%, TAH 3%. Cancer: Cytology 4%, histology 7%,D&C 5% TAH 9%. Unusable material 3%.
Inadequate material: Cytology1, histology 1%, D&C 6%. Miscarriage sampling material:
Cytology 2%. TVS results: The mean endometrial thickness for women with PMB with an
istopathologic diagnosis atrophy was 3,5mm and normal endometrium in women with PMB
of 4mm. No endometrial cancer below an endometrial measurement of 5mm. Endometrial
cancer >6mm with range 6–30mm. It has been claimed that endometrial cavity fluid is
correlated with a high risk of endometrial pathology.
Conclusion: However inadequate material of endometrial sampling and of D&C is one reason for the
inaccuracy in diagnostic endometrial pathology.
