Abstract
2,6-Disubstituted 5-hydroxy-3(2H )-pyridazinone-4-carboxylic acid ethyl esters were synthesized from α-keto esters
via an efficient three-step sequence including hydrazone formation, acylation with
ethyl malonyl chloride, and subsequent Dieckmann cyclization.
Key words
α-keto esters - acylation - hydrazones - Dieckmann cyclization - pyridazinones
References
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