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Synlett 2007(17): 2764-2765  
DOI: 10.1055/s-2007-991080
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© Georg Thieme Verlag Stuttgart · New York

[Hydroxy(tosyloxy)iodo]benzene (HTIB)

Rajesh Kumar*
Department of Chemistry, Kurukshetra University, Kurukshetra, Haryana 136119, India
e-Mail: rajesh_chem12a@rediffmail.com;
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Publication History

Publication Date:
27 September 2007 (online)

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Introduction

[Hydroxy(tosyloxy)iodo]benzene (HTIB), one of the most significant reagents among the family of hypervalent iodine reagents, has been widely used as an effective ­oxidant in the synthesis of various organic compounds. HTIB was first discovered in 1970 by Neiland and Karele. [1] A few years later, Koser and co-workers discovered that HTIB is an efficient reagent in organic synthesis, so in contemporary literature HTIB is often referred to as ‘Koser’s Reagent’.