Abstract
The purpose of this study was to compare biochemical changes and endocrine responses
during an incremental maximal bicycle test in three well-trained 18-year-old patients
with cystic fibrosis (CF) and in three healthy controls. Although the blood concentration
at rest of the white cell count, haptoglobin, phosphorus, urea, creatinine, and uric
acid were somewhat different in the two groups, the CF patients had similar biochemical
changes in response to the exercise compared with the healthy men. The endocrine responses
to exercise seemed to be different between the two groups with regard to changes in
Cortisol, growth hormone, and testosterone concentrations. The differences, however,
were probably caused by differences in age, training situation, and psychological
stress reaction rather than by pathological mechanisms.
Key words
biochemical changes - cystic fibrosis - endocrine response - exercise test