Summary
Background Poxvirus induced molluscum contagiosum is known to occur in children, elderly people
and in patients with the acquired immune deficiency syndrome AIDS.
Patient and methods We report on a 49-year-old patient who presented with a three-month history of multiple
skin-coloured prominent warts on his right upper and lower eyelid. On examination,
the warts showed a central cavity and measured 2-6 mm in diameter. For his “mixed
connective tissue disease” (MCTD) the patient took methotrexate in a weekly dosage
of 7.5 mg since 3 years. Diagnosis of MCTD was made 7 years before. The warts were
excised and studied histopathologically. One year postoperatively, there was no recurrence
of the lesions.
Conclusion Drug induced immunosuppression as with methotrexate may be associated with multiple
periocular lesions due to molluscum contagiosum.
Schlüsselwörter
Molluscum contagiosum - Immunsuppression - Lidtumoren - Methotrexat - Sharp Syndrom
- AIDS
Key words
Molluscum contagiosum - immunosuppression - eyelid tumors - mixed connective tissue
disease - methotrexate - sharp syndrome - acquired immune deficiency syndrome
