Abstract
Objective: Closed repair of pectus excavatum (PE), also known as the Nuss procedure, has become
more popular recently, and whether this operation results in true cardiac improvement
as opposed to postoperative physical rehabilitation or a psychological effect deserves
examination. Methods: Ten PE patients (8 males, 2 females) aged 4 to 54 years (average, 19.6 ± 14 years)
were prospectively evaluated using preoperative computed tomography (CT) scan, pulmonary
function studies, electrocardiogram and transthoracic echocardiographic (TTE) evaluation
of cardiac function. The same studies were repeated at 3 months post bar placement.
In addition, intraoperative transesophageal echocardiogram (TEE) was done to measure
the procedure-related values of the cardiac chamber and functional indices before
and after turning of the pectus bar. Results: Statistically significant changes in the pectus index, obtained by dividing the internal
transverse distance of the thorax by the vertebral-sternal distance at the most depressed
portion of the deformity, were noted after surgery, decreasing from 5.06 ± 1.46 to
3.55 ± 0.48 (p < 0.05). Most patients with previously abnormal electrocardiograms showed a normal
pattern after surgical repair (p < 0.05). Five subjects in the PE group (50 %) showed mitral valve prolapse in TTE
and 4 of them had mitral regurgitation. However, these valve patterns could not be
corrected after surgical repair of the chest wall deformity (p = 0.25). The cardiac chamber and the function of the right ventricle were evaluated
by intraoperative TEE and showed significantly increased values after retrosternal
dissection and post-turning of the pectus bar. Conclusion: The data of this study supports the concept that closed repair directly contributes
to hemodynamic improvement.
Key words
thoracic surgery - pectus excavatum - transesophageal echocardiogram
References
- 1
Creswick H A, Stacey M W, Kelly R E. et al .
Family study of the inheritance of pectus excavatum.
J Pediatr Surg.
2006;
41
1699-1703
- 2
Morshuis W J, Folgering H T, Barentsz J O, Cox A L, van Lier H J, Lacquet L K.
Exercise cardiorespiratory function before and one year after operation for pectus
excavatum.
J Thorac Cardiovasc Surg.
1994;
107
1403-1409
- 3
Mocchegiani R, Badano L, Lestuzzi C, Nicolosi G L, Zanuttini D.
Relation of right ventricular morphology and function in pectus excavatum to the severity
of the chest wall deformity.
Am J Cardiol.
1995;
76
941-946
- 4
Kowalewski J, Brocki M, Dryjanski T, Zolynski K, Koktysz R.
Pectus excavatum: increase of right ventricular systolic, diastolic, and stroke volumes
after surgical repair.
J Thorac Cardiovasc Surg.
1999;
118
87-92
92-93
- 5
Peterson R J, Young Jr W G, Godwin J D, Sabiston Jr D C, Jones R H.
Noninvasive assessment of exercise cardiac function before and after pectus excavatum
repair.
J Thorac Cardiovasc Surg.
1985;
90
251-260
- 6
Guntheroth W G, Spiers P S.
Cardiac function before and after surgery for pectus excavatum.
Am J Cardiol.
2007;
99
1762-1764
- 7
Quigley P M, Haller Jr J A, Jelus K L, Loughlin G M, Marcus C L.
Cardiorespiratory function before and after corrective surgery in pectus excavatum.
J Pediatr.
1996;
128
638-643
- 8
Wynn S R, Driscoll D J, Ostrom N K. et al .
Exercise cardiorespiratory function in adolescents with pectus excavatum. Observations
before and after operation.
J Thorac Cardiovasc Surg.
1990;
99
41-47
- 9
Nuss D, Kelly R E, Croitoru D P.
A 10 year review of a minimally invasive technique for correction of pectus excavatum.
J Pediatr Surg.
1998;
33
545-552
- 10
Rosenzweig M S, Huang M T.
Left ventricular diverticula with mitral valve prolapse and pectus excavatum.
NY State J Med.
1982;
82
1097-1099
- 11 Cooper C B, Storer T W. Exercise Testing and Interpretation: A Practical Approach. London,
UK; Cambridge University Press 2001
- 12
Andres A M, Hernandez F, Martinez L. et al .
Cardiac function alterations in pectus excavatum.
Cir Pediatr.
2005;
18
192-195
- 13
Malek M H, Berger D E, Marelich W D, Coburn J W, Beck T W, Housh T J.
Pulmonary function following surgical repair of pectus excavatum: a meta-analysis.
Eur J Cardiothorac Surg.
2006;
30
637-643
- 14
Liu W, Hu T, Wei F.
A study of relation of cardiac function and deformity degree in children with pectus
excavatum.
Zhonghua Wai Ke Za Zhi.
1995;
33
473-475
- 15
Rowland T, Moriarty K, Banever G.
Effect of pectus excavatum deformity on cardiorespiratory fitness in adolescent boys.
Arch Pediatr Adolesc Med.
2005;
159
1069-1073
- 16
Malek M H, Fonkalsrud E W, Cooper C B.
Ventilatory and cardiovascular responses to exercise in patients with pectus excavatum.
Chest.
2003;
124
870-882
- 17
Bawazir O A, Montgomery M, Harder J, Sigalet D L.
Midterm evaluation of cardiopulmonary effects of closed repair for pectus excavatum.
J Pediatr Surg.
2005;
40
863-867
- 18
Bevegård S.
Postural circulatory changes at rest and during exercise in patients with funnel chest,
with special references to factors affecting stroke volume.
Acta Med Scand.
1962;
171
695-713
- 19
Clausner A, Clausner G, Basche M. et al .
Importance of morphological findings in the progress and treatment of chest wall deformities
with special reference to the value of computed tomography, echocardiography and stereophotogrammetry.
Eur J Pediatr Surg.
1991;
1
291-297
- 20
Yalamanchili K, Summer W, Valentine V.
Pectus excavatum with inspiratory inferior vena cava compression: a new presentation
of pulsus paradoxus.
Am J Med Sci.
2005;
329
45-47
- 21
Soderstrom M J, Gilson S D, Gulbas N.
Fatal reexpansion pulmonary edema in a kitten following surgical correction of pectus
excavatum.
J Am Anim Hosp Assoc.
1995;
31
133-136
Dr. Yung-Chie Lee
Department of Traumatology and Surgery
National Taiwan University Hospital
No. 7, Chung-Shan S. Rd
Taipei 100
Taiwan – Republic of China
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