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Synfacts 2008(3): 0219-0219
DOI: 10.1055/s-2008-1042657
DOI: 10.1055/s-2008-1042657
Synthesis of Natural Products and Potential Drugs
© Georg Thieme Verlag Stuttgart · New York
Synthesis of Quadrangularin A and Pallidol
S. A. Snyder*, A. L. Zografos, Y. Lin
Columbia University, New York, USA
Weitere Informationen
Publikationsverlauf
Publikationsdatum:
21. Februar 2008 (online)
Significance
Resveratrol-based oligomers are produced combinatorially by plants in response to environmental stress. Snyder and co-workers report that the core structure A can be transformed to every member of the family by simply altering reagents and reaction conditions. Pallidol, quadrangularin, ampelopsins D and F, paucifloral F, and hemsleyanol E were all synthesized by related cationic cyclization cascades.