Synfacts 2008(4): 0406-0406  
DOI: 10.1055/s-2008-1042827
Metal-Mediated Synthesis
© Georg Thieme Verlag Stuttgart · New York

Palladium-Catalyzed Cross-Coupling of Triarylbismuths with Acyl Chlorides

Contributor(s): Paul Knochel, Andrei Gavryushin
M. L. N. Rao*, V. Venkatesh, D. Banerjee
Indian Institute of Technology, Kanpur, India
Further Information

Publication History

Publication Date:
19 March 2008 (online)


Direct synthesis of isomeric ketones under Friedel-Crafts acylation conditions can easily be challenging. Thus, the reaction of organometallic reagents with acyl chlorides often is a better alternative. Arylbismuth compounds can be readily prepared via standard procedures, they are stable and easy to handle. The described acylation reaction offers a simple, atom-efficient synthetic way to various functionalized aryl ketones.