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Neuropediatrics 1984; 15: 24-27
DOI: 10.1055/s-2008-1052378
DOI: 10.1055/s-2008-1052378
Pathophysiological Aspects of Central and Peripheral Myelin Lesions
Further Information
Publication History
Publication Date:
19 March 2008 (online)
Abstract
The results of nerve conduction velocities, evoked potentials and EEGs in adrenoleukodystrophy, metachromatic leukodystrophy and Pelizaeus Merzbacher's disease are discussed. As shown on the example of four own cases with metachromatic leukodystrophy, the slowing of nerve conduction velocities and the latency prolongation of evoked potentials components or loss of evoked potential components is dependent on the type of MLD (infantile and juvenile) and of the duration of the disease. The pathophysiology of the slowed peripheral and central impulse conduction is discussed.
Key words
Hereditary myelin lesions - Nerve conduction velocity - Evoked potentials - EEG