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Neuropediatrics 1987; 18(1): 37-39
DOI: 10.1055/s-2008-1052432
CASE REPORTS

© Georg Thieme Verlag KG Stuttgart · New York

Empty Sella Associated with Inappropriate TSH Secretion

W. H. Hoffman1 , B. G. England2 , Lily M. Gomez3 , G.  Rosculet4 , R. R. Gala5
  • 1Department of Pediatrics, Section of Pediatric Endocrinology, Medical College of Georgia, Augusta, Georgia 30912, USA
  • 2Department of Pathology and Ligand Assay Laboratory, University of Michigan School of Medicine, Ann Arbor, Michigan, USA
  • 3Department of Pediatrics, Medical College of Georgia, Augusta, Georgia 30912, USA
  • 4Endocrine Laboratory, Children's Hospital of Michigan, Detroit, Michigan, USA
  • 5Department of Physiology, Wayne State University School of Medicine, Detroit, Michigan, USA
Further Information

Publication History

Publication Date:
19 March 2008 (online)

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Abstract

A child diagnosed with long-standing primary hypothyroidism at age 10 and subsequent pseudotumor cerebri after initiation of thyroid therapy developed an empty sella and inappropriate thyrotropin secretion. No other evidence of thyroid hormone resistance was evident nor was there evidence of other endocrine dysfunction. This case confirms previous reports of a relationship between autoimmune thyroid disease, pseudotumor cerebri, empty sella and inappropriate anterior pituitary function.

Key words

Empty sella - Pseudotumor cerebri - Primary hypothyroidism - Inappropriate thyrotropin

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