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Neuropediatrics 1981; 12(4): 374-381
DOI: 10.1055/s-2008-1059668
Case reports

© Georg Thieme Verlag KG Stuttgart · New York

THE POSSIBLE ADJUVANT ROLE OF BORDETELLA PERTUSSIS AND PERTUSSIS VACCINE IN CAUSING SEVERE ENCEPHALOPATHIC ILLNESS: A PRESENTATION OF THREE CASE HISTORIES

N. P. C. Cavanagh , E. M. Brett , W. C. Marshall , J.  Wilson
  • The Departments of Neurology and Virology, Hospital for Sick Children, Great Ormond Street, London WC1N 3JH, England
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Publication History

Publication Date:
19 March 2008 (online)

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Abstract

The clinical and some laboratory details of three children who had severe neurological sequelae after either infection with Bordetella pertussis or immunisation with diphtheria, tetanus and pertussis vaccine and oral polio vaccine are reported. Each of these patients had had a recent or concurrent viral illness. The severity of their encephalopathic illness may have been due to an adjuvant role of B. pertussis or a component of the vaccines they received.

Key words

Diphtheria - tetanus - pertussis - oral polio vaccines - adjuvant encephalopathic illness - recent or concurrent viral illness

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