Pd(II)-Catalyzed Hydrosilylation Using Silicon-Stereogenic Silanes

Significance

This report describes the possibilities of utilizing configurationally stable, chiral silicon compounds for intermolecular chirality transfer through Pd-catalyzed hydrosilylation of alkenes. The authors have carried out a series of highly elaborated experiments using various triorganosilanes and norbornene- and norbornadiene-type substrates to showcase the efficiency of the methodology. Interestingly, both cylic and acyclic silane substrates provide the products with high level of diastereoselectivity. Additionally, chiral silanes react in a highly enantioselective fashion.