Journal of Pediatric Neurology, Table of Contents Journal of Pediatric Neurology 2011; 09(01): 097-099DOI: 10.3233/JPN-2010-0438 Georg Thieme Verlag KG Stuttgart – New YorkKocher-Debre-Semelaigne syndrome with exceptionally elevated creatine phosphokinase levels Authors Author Affiliations Rajniti Prasad a Department of Pediatrics, Institute of Medical Sciences, Banaras Hindu University, Varanasi, Uttar Pradesh, India Roopali Mittal a Department of Pediatrics, Institute of Medical Sciences, Banaras Hindu University, Varanasi, Uttar Pradesh, India Om Prakash Mishra a Department of Pediatrics, Institute of Medical Sciences, Banaras Hindu University, Varanasi, Uttar Pradesh, India Subject Editor: Recommend Article Abstract PDF Download(opens in new window) Abstract A 13-year-old female child presented to us with enlargement of calf muscle of both lower limb and later diagnosed as hypothyroid myopathy i.e. Kocher-Debre-Semelaigne syndrome. She had extremely high levels of serum creatine phosphokinase. With thyroid replacement therapy, her creatine phosphokinase and myopathy resolved in 3 months. Keywords KeywordsHypothyroidism - myopathy - creatine phosphokinase PDF (35 kb)
