Intra-articular injections of autologous platelet concentrates in dogs with surgical reparation of cranial cruciate ligament rupture

R. F. Silva; J. U. Carmona; C. M. F. Rezende

doi:10.3415/VCOT-12-06-0075

Veterinary and Comparative Orthopaedics and Traumatology, Inhaltsverzeichnis

Vet Comp Orthop Traumatol 2013; 26(04): 285-290
DOI: 10.3415/VCOT-12-06-0075

Original Research

Schattauer GmbH

Intra-articular injections of autologous platelet concentrates in dogs with surgical reparation of cranial cruciate ligament rupture

A pilot study

R. F. Silva

¹Departamento de Clinica e Cirurgia Veterinárias, Universidade Federal de Minas Gerais, Brasil

²Grupo de Investigación Terapia Regenerativa, Departamento de Salud Animal, Universidad de Caldas, Colombia

,

J. U. Carmona

²Grupo de Investigación Terapia Regenerativa, Departamento de Salud Animal, Universidad de Caldas, Colombia

,

C. M. F. Rezende

¹Departamento de Clinica e Cirurgia Veterinárias, Universidade Federal de Minas Gerais, Brasil

› Institutsangaben

Abstract

Summary

Objective The objective of this study was to evaluate by clinical, radiographic, and force plate gait analyses the effect of postsurgical intra-articular injections of autologous platelet concentrates (PC) in a small group of dogs with cranial cruciate ligament (CCL) rupture.

Methods The ten dogs used in this study were initially presented with CCL rupture and underwent ligament replacement surgery by fascia lata autograft guided by arthroscopy. Six dogs received three intra-articular injections of PC (PC group); one dose was injected immediately after surgery, and two additional doses were injected at two-week intervals. The remaining four dogs received only nutraceuticals (control group). All dogs were evaluated by clinical examination, serial radiography, and force plate gait analyses at monthly intervals up to 90 days.

Results The clinical follow-up of the PC-treated group indicated a better outcome than the control group. Radiographic evaluation was not conclusive. Values of peak vertical reaction force and vertical impulse of the affected limbs were only significantly larger on the 90th postoperative day in the PC group compared to the control group.

Clinical significance Our results indicate that autologous PC might improve functional outcome after intra-articular cranial cruciate ligament repair. The effect of PC when using other repair procedures warrants additional studies.

Keywords

Autologous platelet concentrates - cranial - cruciate ligament - force plate gait analyses - dog

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Referenzen

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