Early acetabular cartilage wear following hemiarthroplasty: An ovine model

John R. Field; Stuart A. Callary; Lucian B. Solomon; Roumen Stamenkov; Margaret A. McGee; Donald W. Howie

doi:10.3415/VCOT-15-04-0063

Veterinary and Comparative Orthopaedics and Traumatology, Inhaltsverzeichnis

Vet Comp Orthop Traumatol 2016; 29(02): 125-130
DOI: 10.3415/VCOT-15-04-0063

Original Research

Schattauer GmbH

Early acetabular cartilage wear following hemiarthroplasty: An ovine model

Authors

John R. Field

¹Centre for Orthopaedic and Trauma Research, University of Adelaide, South Australia
Stuart A. Callary

¹Centre for Orthopaedic and Trauma Research, University of Adelaide, South Australia
Lucian B. Solomon

¹Centre for Orthopaedic and Trauma Research, University of Adelaide, South Australia
Roumen Stamenkov

¹Centre for Orthopaedic and Trauma Research, University of Adelaide, South Australia
Margaret A. McGee

¹Centre for Orthopaedic and Trauma Research, University of Adelaide, South Australia
Donald W. Howie

¹Centre for Orthopaedic and Trauma Research, University of Adelaide, South Australia

Abstract

Summary

Objectives: Hemiarthroplasty induces degenerative changes in the hip joint, which are difficult to evaluate in vivo. Radiostereometric analysis (RSA) is a radiographic measurement technique that has recently been used to measure acetabular cartilage wear in vivo. The aim of the study was to measure acetabular cartilage wear, using this technique, in an ovine model during the first 14 weeks post-implantation.

Methods: Measurements of three-dimensional femoral head migration, combined with visual assessments at necropsy and safranin O staining for cartilage integrity, were undertaken.

Results: Mean femoral head migration during the first six weeks was 0.525 mm in the medial, 0.144 mm in the cranial, and 0.517 mm in the dorsal direction. The majority of this migration was confirmed to be cartilage wear in the medial and dorsal aspects of the acetabulum at necropsy and with subsequent histological evaluation depicting significant cartilage degeneration.

Clinical significance: Radiostereometric analysis is the current gold standard technique for in vivo assessment of implant migration following total hip replacement. This study has utilized RSA to quantify the amount of early cartilage wear in vivo, which was supported by ex vivo evaluations. Accurately measuring the amount of cartilage wear will allow future studies to compare component material and design characteristics prior to clinical use.

Keywords

Hemiarthroplasty - acetabular cartilage - radiostereometric analysis - cartilage wear

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Referenzen

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