Abstract
Objectives: The purpose of this study was to establish the role of the liquid embolic agent,
ONYX, in the treatment of cranial dural arteriovenous fistulae (DAVFs) and to redefine
the indications, techniques and outcomes of treatment with ONYX. Materials and
Methods: This is a retrospective study of 25 DAVF patients who underwent endovascular
treatment with ONYX between February 2006 and July 2008. All patients of DAVF presenting
in this period were treated with ONYX. Results: Anatomic cure (i.e., complete angiographic closure of the fistula) was achieved
in a single session and through a single arterial pedicle injection in 21 out of 25
patients (cure rate of 84%). Out of four patients with residual fistulae, one achieved
cure that was evident on a control angiogram obtained at 3 months while three had
no vascular access for further embolization and so were referred for radiosurgery.
There was only one recurrence seen in angiograms obtained at the end of one year and
this patient was re-embolized successfully with ONYX. Complications were seen in two
patients. Conclusion: ONYX embolization of DAVFs has revolutionized the endovascular treatment of DAVFs,
achieving high cure rates in a single session with minimal complications. Transarterial
ONYX embolization should be the first option for all locations, except cavernous DAVFs.
Keywords
Dural arteriovenous fi stula - embolization - ONYX - technique